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The complete BATMAN: CONTAGION storyline is available for the first time ever, along with chapters that lead into the thrilling confrontation with the mastermind behind the outbreak in BATMAN: LEGACY. A mysterious and lethal virus is unleashed on the unknowing inhabitants of Gotham City, causing excruciating pain and ultimately death within 48 hours of contact. Batman, Robin and Nightwing must race to contain the chaos while finding a cure with the help of unlikely allies Azrael, Huntress, Catwoman and Poison Ivy. But can the Dark Knight and his team of vigilantes stop an invisible enemy? And what happens when one of them is infected? Collects AZRAEL 15-16, BATMAN 529, BATMAN CHRONICLES 4, BATMAN: SHADOW OF THE BAT 48-49, CATWOMAN 31-35, DETECTIVE COMICS 695-696 and ROBIN 27-30."
If you're a BatFan read it but I wouldn't consider it seminal. This came out 2 years after Richard Preston's The Hot Zone, which was likely an inspiration. The Hot Zone is a much better and much more suspenseful read.
Batman: Contagion | 
so-so
